Uncertainty analysis of tumour absorbed dose calculations in molecular radiotherapy

Uncertainty analysis of absorbed dose calculations from thermoluminescence dosimeters.

Thermoluminescence dosimeters (TLD) are widely used to verify absorbed doses delivered from radiation therapy beams. Specifically, they are used by the Radiological Physics Center for mailed dosimetry for verification of therapy machine output. The effects of the random experimental uncertainties of various factors on dose calculations from TLD signals are examined, including: fading, dose resp...

Development and Evaluation of an Independent System for Absorbed Dose Calculations in Radiotherapy

Photon Cross Section Data in Absorbed Dose Calculations

Air kerma data and the relative response of the new HPA TLD are calculated for Narrow Series X-ray distribution and Cs photon sources using the general purpose Monte Carlo code MCNP5, and the results are compared to those obtained using its predecessor, MCNP4c2. It is found that the results differ at low energies (< 0.1 MeV) by up to ~10 %. This disparity is mainly ascribed to differences in th...

Comments on 'Converting absorbed dose to medium to absorbed dose to water for Monte Carlo based photon beam dose calculations'.

Current clinical experience in radiation therapy is based upon dose computations that report the absorbed dose to water, even though the patient is not made of water but of many different types of tissue. While Monte Carlo dose calculation algorithms have the potential for higher dose accuracy, they usually transport particles in and compute the absorbed dose to the patient media such as soft t...

Calculations of absorbed dose and energy dependent of small-scale dosimeters for photons beam therapy

In this study, the energy dependency for dosimeters of air ionization chambers, lithium fluoride, silicon and plastic scintillator has been studied using the MCNPX Monte Carlo simulation code and simulated for gamma energy in the range of radiotherapy energy. The simulation results show that the response of each of the dosimeters for gamma photon beams in the energy range of 0.2 to 20 MeV varie...